Recent Articles on Andrographis sp.

How to use Andrographis paniculata

Q:- I'm interested in finding how to use Andrographis paniculata as I have just started growing some. What parts are used for what purpose and the methods used as well as dosages. For instance, is the fluid extracted by crushing the leaves and what amount of this would be used as a dose?



A:- Please have a look at pharmacology and some literature of A. paniculata. This will give you a clear picture of the medicinal properties associated with this wonderful herb.



Then, regarding the useful parts, all parts above ground can be used to prepare a decoction. For instance, take 2-3 leaves and boiled in one glass of water for 5-10 min. Add enough honey or sugar and drink. You can finish it off at once or consume in divided quantities. This would be an ideal choice during onset of cold.



Another way of consuming the herb is to put 2-3 leaves in wisky or barndy, and use it after a day or two. This sounds scientificallly more correct (similar to the methanolic extraction of andrographolide, see a study on this aspect).



Some useful links


Integrative Way: Avoiding colds and flu

Original article : http://www.sacbee.com/107/story/85391.html

Q: I get sick every holiday season. This year, I don't want to catch a cold and ruin my vacation. How can I prevent a cold from coming on? I already take echinacea and zinc.

A: We all know the basics for staying healthy during the cold and flu season:

• Maintain good hygiene.

• Wash hands frequently.

• Avoid contact with people who are ill.

• Manage your stress levels and optimize your sleep.

• Get a flu shot, especially if you are over 50 or if you have a medical condition that might affect your immune system, including heart/lung disease or diabetes.

Some alternative therapies that may offer benefits:

• Panax ginseng may improve the response you get from the flu vaccine; should you get the flu, the herb elderberry may reduce your symptoms.

• Echinacea has been shown to reduce the duration of cold symptoms; another herb, andrographis, as well as vitamin C and zinc lozenges or nasal spray, may do the same.

But here is some interesting information that you may not know:

Strengthening your social ties may help prevent the common cold. A study published in the Journal of the American Medical Association in 1997 covered the effects of relationships on the common cold. Researchers exposed 276 healthy volunteers to the cold virus (rhinovirus). The volunteers were questioned about 12 types of relationships: parental, childhood, friends, groups, etc.

Those who scored only three out of 12 in their relationship questionnaire developed cold symptoms four times as frequently as those with strong social ties. Therefore, we suggest that you stay connected with those you love this holiday season, and mend relationships that need repair. The payoff may be worth it in terms of your physical health.

Protective activity of andrographolide

Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice


Microbiology and Immunology Laboratory, Department of Human Physiology with Community Health, Vidyasagar University, Midnapore 721 102, West Bengal, India; Plant Biotechnology Laboratory, Department of Biotechnology, IIT, Kharagpur 721 302, West Bengal, India.

To find out the active principles against ethanol-induced toxicity in mice, Andrographis paniculata Nees. (Ap) was chosen and isolated andrographolide (ANDRO) and arabinogalactan proteins (AGPs). ANDRO was detected by HPTLC, FTIR and quantified by HPLC (10mg/g of Ap powder). AGPs was detected by beta-glucosyl Yariv staining of SDS-PAGE gel, FTIR and quantified by single radial gel diffusion assay with beta-glucosyl Yariv reagent (0.5mg/g Ap powder). The mice are pretreated intra-peritoneally (i.p.) with different doses (62.5, 125, 250, and 500mg/kg) of body weight of mice] of ANDRO and AGPs for 7 days and then ethanol (7.5g/kg of body weight) was injected, i.p. Besides, silymarin was used as standard hepatoprotective agent for comparative study with ANDRO and AGPs. The ameliorative activity of ANDRO and AGP against hepatic renal alcohol toxicity was measured by assessing GOT, GPT, ACP, ALP and LP levels in liver and kidney. It has been observed that pretreatment of mice with ANDRO and AGPs at 500mg/kg of body weight and 125mg/kg of body weight respectively could able to minimize the toxicity in compare to ethanol treated group as revealed by the different enzymatic assay in liver and kidney tissues and the results were comparable with silymarin. Hence, out of several ill-defined compounds present in Ap, ANDRO and AGPs are the potential bioactive compounds responsible for protection against ethanol-induced toxicity.

http://www.ncbi.nlm.nih.gov/entrez/
PMID: 17127022